{"id":90,"date":"2011-11-30T21:31:44","date_gmt":"2011-11-30T21:31:44","guid":{"rendered":"http:\/\/www.marhystin-gundogs.co.uk\/wordpress\/?page_id=90"},"modified":"2020-05-29T09:28:13","modified_gmt":"2020-05-29T09:28:13","slug":"centronuclear-myopathy","status":"publish","type":"page","link":"https:\/\/www.marhystin-gundogs.co.uk\/?page_id=90","title":{"rendered":"Centronuclear Myopathy"},"content":{"rendered":"<h1>CNM- (Centronuclear Myopathy)<\/h1>\n<p><strong>CNM- (Centronuclear Myopathy)<\/strong><\/p>\n<p><strong>Clinical features of hereditary myopathy in Labrador Retrievers include hypotonia, generalized muscle weakness, abnormal postures, stiff hopping gait, exercise intolerance and increased collapse when exposed to cold. Hereditary myopathy in Labrador Retrievers is an inherited autosomal recessive trait. This means that a dog can be clear (homozygous normal), affected, or a carrier (heterozygous). The carriers can spread the diseased gene in the population. Therefore, reliable information on non-affected dogs is the key to controlling this disease.<\/strong><br \/>\n<strong> The genetic defect leading to the disease has been identified. By DNA testing, the responsible mutation can be shown directly. This method provides a very high accuracy test and can be done at any age. It offers the possibility to distinguish not only between affected and clear dogs, but also to identify clinically healthy carriers. This is an essential information for controlling the disease in the breed, as carriers are able to spread the disease in the population, but can not be identified by means of common laboratory diagnostic<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CNM- (Centronuclear Myopathy) CNM- (Centronuclear Myopathy) Clinical features of hereditary myopathy in Labrador Retrievers include hypotonia, generalized muscle weakness, abnormal postures, stiff hopping gait, exercise intolerance and increased collapse when exposed to cold. Hereditary myopathy in Labrador Retrievers is an inherited autosomal recessive trait. This means that a dog can be clear (homozygous normal), affected, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":391,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-90","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Marhystin Gundogs Scotland, bred with passion and pride.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.marhystin-gundogs.co.uk\/?page_id=90\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Marhystin Gundogs | Quality gundogs with excellent temperament and health\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta 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08:26:37","updated":"2025-12-18 09:58:29","seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.marhystin-gundogs.co.uk\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.marhystin-gundogs.co.uk\/?page_id=391\" title=\"health &amp; dna tests\">health &amp; dna tests<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tCentronuclear Myopathy\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.marhystin-gundogs.co.uk"},{"label":"health &#038; dna tests","link":"https:\/\/www.marhystin-gundogs.co.uk\/?page_id=391"},{"label":"Centronuclear 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